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- W2393048775 abstract "Objective To investigate the role of gene C/EBPβ in idiopathic congenital talipes equinovarus(ICTEV)and give the proposal of the research process in the cell line selection.Methods The expression of C/EBPβ mRNA and protein was assayed in human muscle tissue of ankle including ICTEV patients'and normal controls'by RT-PCR,immunohistochemistry and immunofluorescence respectively.Results The average optical density(AOD)ratio for C/EBPβ mRNA/β-Actin mRNA was much lower in ICTEV patients than in normal controls(0.05).The results of C/EBPβ protein were the same as for mRNA and morphological changes in ICTEV were accorded with fibrosis in tissues and organs and general fibroelastosis.Conclusion Changes of C/EBPβ gene expression may be related to the development of talipes equinovarus malformation which might exhist the fibrosis of interior foot." @default.
- W2393048775 created "2016-06-24" @default.
- W2393048775 creator A5008889596 @default.
- W2393048775 date "2011-01-01" @default.
- W2393048775 modified "2023-09-27" @default.
- W2393048775 title "Expression and distribution of C/EBPβ mRNA and protein in ankle muscle tissue of idiopathic congenital talipes equinovarus patients" @default.
- W2393048775 hasPublicationYear "2011" @default.
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