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- W2393051122 abstract "Objective To evaluate rational use of antibiotics for hernioplasty in perioperative period by interventioncontrol study in order to provide a foundation for the clinical antibiotic use and management. Methods The data of the preventive use of antibiotics for hernia patients from January to October, 2010 in perioperative period were collected and compared. Interventions on patients from January to October, 2011 were carried out. Results In the intervention group, the fi rst three antibiotics used were changed from azlocillin, mezlocillin and aztreonam before intervention to cefazolin, clindamycin and azlocillin after intervention. Before intervention, antibiotics were fi rst used after surgery for surgical prophylaxis, while after intervention, antibiotics were fi rst used within 30 minutes before surgery or at the start of induction of anesthesia. The preventive medication time decreased from(3.50 ± 2.07) days to(0.88 ± 1.07) days(t'=14.601, P=0.000), the hospitalization days of post-surgery decreased from(5.17 ± 1.90) days to(3.77 ± 1.61) days(t'=7.313, P=0.000), the cost of antibiotics decreased from(342.39 ± 415.50) yuan to(54.08 ± 80.83) yuan(t'=8.831, P=0.000), the percentage of the cost of antibiotics in expenses for medicine declined from(47.53 ± 25.51)% to(12.49 ± 13.46)%(t'=15.776, P=0.000), and the percentage of the cost of antibiotics in hospitalization expenses declined from(6.59 ± 5.49)% to(1.07 ± 1.35)%(t'=12.662, P=0.000). The difference in inappropriate use of antibiotic drugs before and after prevention, such as choice of preventive drugs, preoperative medication occasion, course of postoperative medication and no indication of drug combination, had statistical signifi cances(P 0.05). Conclusion The intervention-control study shows that the rational use of antibiotics for hernioplasty in perioperative period can be improved, and the average hospitalization days and the cost of antibiotics can be reduced by intervention." @default.
- W2393051122 created "2016-06-24" @default.
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- W2393051122 date "2014-01-01" @default.
- W2393051122 modified "2023-09-28" @default.
- W2393051122 title "Antibiotics Use in Perioperative Period of Hernioplasty by Intervention-control Study" @default.
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