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- W2393061332 abstract "Objective To explore the diagnostic and prognostic value of the joint measurements of serium amylase(AMY),lipase(LPS),C-reactive protein(CRP) and interleukin-6(IL-6) in patients with acute pancreatitis(AP).Methods The levels of serum AMY,LPS,CRP and IL-6 in 50 patients with AP,including 28 patients with mild acute pancreatitis(MAP) and 22 patients with severe acute pancreatitis(SAP),and 50 patients with non-pancreatitis acute abdomen(NAA) and 50 healthy people were measured.Then we tested the serum levels of CRP and IL-6 in 50 patients with AP on the third,the fifth and the seventh day after admission.Results The serum levels of AMY,LPS and CRP in the patients with AP on the admission day were significantly higher than those of the patients with NAA and healthy controls(P0.01),The serum level of IL-6 level in the patients with SAP was substantially higher than that of the healthy controls(P0.01),The serum levels of AMY,CRP and IL-6 in the patients with NAA were significantly higher than those of the healthy controls(P0.01),However,the result of the serum level of LPS in the patients with NAA and the healthy controls was not significantly different(P0.05).The serum levels of CRP and IL-6 in the patients with SAP were significantly higher than those of the patients with MAP,but the result of the serum levels of AMY and LPS in the patients with SAP and MAP was not significantly differenct(P0.05).The highest levels of serium CRP and IL-6 in the patients with SAP were displayed on the third day after admission.Serium CRP and IL-6 levels in the patients with SAP were higher than those in patients with MAP at the same period(P0.01).Serium CRP and IL-6 levels in the patients with SAP and MAP on the seventh day after treatment were significantly lower than the those of the same group on the admission day(P0.01).The sensitivity,specificity and diagnosis of the joint detection of serum AMY,LPS,CRP and IL-6 levels were obviously better than those of a single measurement(P0.01).Conclusion The joint detection of serum AMY,LPS,CRP and IL-6 levels was helpful for the early diagnosis,and the judgement of the severity of disease,observation of therapeutic effect and prognosis in patients with AP." @default.
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- W2393061332 date "2011-01-01" @default.
- W2393061332 modified "2023-09-23" @default.
- W2393061332 title "The diagnostic and prognostic values of the joint detection of 4 serum indicators in patients with acute pancreatitis" @default.
- W2393061332 hasPublicationYear "2011" @default.
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