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- W2393065387 abstract "Objective To evaluate the effects and safety of transplantation of peripheral blood stem cells(PBSCs) in coronary artery bypassing grafting(CABG) for the treatment coronary heart disease.Methods Six patients who had suffered from coronary heart disease with myocardial infarction were reselected.PBSCs were transplanted immediately following CABG.Autologous PBSCs were isolated and cultured for 23 weeks.And 1.1~1.4×106 were transplanted through intra coronary way.Cardiac functions were determined by 99m methoxy iso butyl isonitile(99mTcMIBI),2D echocardiogram and ECG Holter monitor 2 weeks and three months before and after the operation respectively.Results Left ventricular ejection fraction(LVEF) was significantly increased by 15.6%(12.1%~20.6%) and left ventricular diastolic diameter(LVDd) reduced by 5.5mm(-2~9mm) through 2D echocardiogram and myocardial perfusion significantly improved in infarction site through 99mTcMIBI.Neither obvious arrhythmia nor complications were observed during the 6~12 months follow up in all the 6 patients.Conclusion The preliminary study showed that in the patients who suffered form coronary heart disease complicated with myocardial infarction,transplantation of PBSCs could restrain the reconstruction of left ventricle and improve cardiac function and cardiac perfusion without significant complication and arrhythmia during the 6~12 months follow up." @default.
- W2393065387 created "2016-06-24" @default.
- W2393065387 creator A5047160585 @default.
- W2393065387 date "2007-01-01" @default.
- W2393065387 modified "2023-09-25" @default.
- W2393065387 title "Clinical Research for Treatment of Coronary Heart Disease with Peripheral Blood Stem Cells Transplantation in CABG" @default.
- W2393065387 hasPublicationYear "2007" @default.
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