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- W2393080068 abstract "Objective To investigate the diagnostic value of glucose-6-phosphate isomerase(GPI) detected by an enzyme linked immunosorbent assay(ELISA) in patients with rheumatoid arthritis(RA).MethodThe GPI was tested by ELISA in serum samples from 120 patients with RA,58 non-RA controls with various rheumatic diseases,and 40 healthy individuals.The level of rheumatoid factor(RF) were also assessed in three groups.ResultsSerum GPI level in RA patients was significantly higher as compared with the other rheumatic diseases and the health controls.There was statistical significant difference between RA patients and patients with other rheumatic diseases(P0.01).Receiver operator curve analysis(ROC) showed an opitium cut off level for GPI at 0.173mg/L.The sensitivity of GPI was 63.33%,the specificity was 77.50% in RA.GPI was associated with RF.GPI was associated with disease activity index by Spearman′s correlation analysis.ConclusionGPI is a valuable diagnostic tool and a useful additional marker for RA.The detection of GPI is useful for the diagnosis of RA,especially combined with RF." @default.
- W2393080068 created "2016-06-24" @default.
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- W2393080068 date "2009-01-01" @default.
- W2393080068 modified "2023-09-24" @default.
- W2393080068 title "Diagnostic value of glucose-6-phosphate isomerase in rheumatoid arthritis" @default.
- W2393080068 hasPublicationYear "2009" @default.
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