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- W2393085305 abstract "Objective To explore molecule biological bases of difference clinical character in gastric carcinoma between young and aged patients.Methods Sixty five gastric carcinomas including 35 young and 30 aged patients were examined immunohistochemically and the serial slides were stained with silver colloid technique. The former data were tested by χ 2 test and the latter were by t test.Results In 65 gastric carcinoma cases, the positive rates for proliferating cell nuclear antigen (PCNA) and the mean argyrophilic proteins associated nucleolar organizer region (AgNOR) count increased as degree of differentiation of the gastric carcinoma decreased, and the mean AgNOR count enhanced as invasive depth increased (P0.05). In the gastric carcinoma cases with the same differentiation, invasive depth or local lymph node metastasis,PCNA positive expression and mean AgNOR count in young patients were significantly higher than those in elderly patients(P0.05).Conclusion PCNA overexpression and the higher mean AgNOR count in young patients with gastric carcinoma than the aged patients indicate the gastric carcinoma cells in young patients may possess much stronger proliferation,invasion and metastasis abilities." @default.
- W2393085305 created "2016-06-24" @default.
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- W2393085305 date "2000-01-01" @default.
- W2393085305 modified "2023-09-23" @default.
- W2393085305 title "Comparative studies on the expressions of PCNA and AgNOR count in gastric carcinoma between young and aged patients" @default.
- W2393085305 hasPublicationYear "2000" @default.
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