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- W2393104540 abstract "Objective: To study the expression of CXCR2 mRNA and protein in villous and decidua tissues of patients with spontaneous abortion.Methods: The location and protein level of CXCR2 in villous and decidua of women with spontaneous abortion and women who had undergone normal selective termination were shown and measured by immunohistochemistry method and image analysis system;The morphological change of villous and decidua of women with spontaneous abortion was observed with light microscope by hematoxylin-eosin staining.Results: CXCR2 protein was mainly located in trophoblastic layer and glands of decidua tissue.The expression of CXCR2 in villous tissues and glands of decidua tissue of the case group was stronger than that of the control group.The expression of CXCR2 showed positive in the cytoplasm of decidual cells,in the case group,but negative in the control group.By hematoxylin-eosin staining we could observe trophoblastic layer got thinner,cells of trophoblastic layer denatured or necrotized,trophoblastic layer cells turned more acidophily,the fibration of villous axis increased in villous of women with spontaneous abortion;Decidua cells lost connection,a part of decidua cells alveolated and turned more acidophily,nucleus dispeared in decidua of women with spontaneous abortion.Conclusions: CXCR2 might take part in the pathologic process of spontaneous abortion by combining with its ligand interleukin-8." @default.
- W2393104540 created "2016-06-24" @default.
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- W2393104540 date "2012-01-01" @default.
- W2393104540 modified "2023-09-23" @default.
- W2393104540 title "Expression of interleukin-8 receptor B in villous tissues anddecidua tissues of patients with spontaneous abortion" @default.
- W2393104540 hasPublicationYear "2012" @default.
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