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- W2393131498 abstract "Objective To explore the etiologic and related investigation of 164 children with short stature.Methods One hundred and sixty-four children were collected,among them 109 were males(66.5%),55 were females(33.5%),the average age was(8.24±2.54) years.All of the children were collected with detailed medical history and with both physical and laboratory examination,and the 20 controls were also included.Results Eighty-six cases(52.4%) were diagnosed as idiopathic short stature(ISS),ncluding constitutional delay of growth and puberty(CDGP) and family short stature(FSS);57 cases(34.8%) were diagnosed as growth hormone deficiency(GHD),serum IGF-1 and IGFBP3 levels in chil-dren with GHD were significantly lower than those in the controls(P0.01);15 cases(9.1%) were diag-nosed as intrauterine growth retardation(IUGR);6 cases(3.7%) were diagnosed as Turners syndrome.Conclusions Idiopathic short stature is a common disease among them,and the second is growth hormone deficiency(GHD),determining serum IGF-1 and IGFBP3 levels could be applied for screening and diagnosis of GHD.For short stature children,correct treatment is according to the pathogeny.After an assessment of short stature has been made,appropriate therapy may be instituted." @default.
- W2393131498 created "2016-06-24" @default.
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- W2393131498 date "2009-01-01" @default.
- W2393131498 modified "2023-09-23" @default.
- W2393131498 title "Etiologic and Related Analysis of 164 Children with Short Stature in Suzhou Area" @default.
- W2393131498 hasPublicationYear "2009" @default.
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