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- W2393142788 abstract "Objective To evaluate the clinical characteristics of patients with acute drug-induced liver injury (DILI).Methods The etiopathogenisis,clinical manifestation and prognosis of 93 patients with acute DILI from January 2011 to December 2012 in our hospital were analyzed retrospectively.Results Many medicines might cause liver injury,and the the main causes were the use of Chinese herbal medicines(40.86%),antituberculosis drugs(21.51%) and antibiotics(12.90%).Many administration routes might cause liver injury,and oral administration was the most common(63.44%).The clinical manifestation included one or more non-specific symptoms such as debility(55.91%),bad appetite(44.09%),abdominal distension(22.58%),nausea and vomiting(21.51%),skin stained yellow(19.35%),diarrhea(11.83%),itch of skin(10.75%),gingiva bleeding or epistaxis(4.30%);but 21 patients(22.58%) showed initial abnormal hepatic function.Liver injury included hepatocellular damage type(65.59%),mixed type(23.66%) and cholestasis type(10.75%).Total of 78 patients(83.87%) were cured after treatment,13 patients were improved,but 2 patients died(2.15%).Conclusions Clinicians should control medication indication seriously and monitor liver function accurately in order to prevent and cure DILI actively." @default.
- W2393142788 created "2016-06-24" @default.
- W2393142788 creator A5059602284 @default.
- W2393142788 date "2013-01-01" @default.
- W2393142788 modified "2023-09-25" @default.
- W2393142788 title "Clinical analysis on 93 cases with acute drug-induced liver injury" @default.
- W2393142788 hasPublicationYear "2013" @default.
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