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- W2393158889 abstract "To investigate the effect of paeonol antagonizing ONOO-(peroxynitrite) on osteoblast differentiation of rat in vitro,osteoblasts of newly born rat's skull were separated and cultured by tissue mass method. ONOO- was produced by chemical synthesis with a quenched flow reactor.Different concentrations of ONOO- were added to cultured osteoblast system in vitro.In different incubation time-phase,PNPP was used to detect the activity of ALP,protein was measured by Lowry,And different concentrations of paeonol were used to antagonize the effect of ONOO- (1000 μmol/L).Different concentrations of ONOO-(50～1000 μmol/L ) could inhibit the activity of ALP to effect osteoblast differentiation.High concentration of paeonol(10 -3～10 -6mol/L)could eliminate the inhibiting effect of ONOO- (1000 μmol/L) on ALP activity,and antagonize the inhibiting effect of ONOO- on osteoblast differentiation." @default.
- W2393158889 created "2016-06-24" @default.
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- W2393158889 date "2005-01-01" @default.
- W2393158889 modified "2023-09-25" @default.
- W2393158889 title "Effect of Paeonol on Inhibition of Peroxynitrite on Osteoblast Differentiation" @default.
- W2393158889 hasPublicationYear "2005" @default.
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