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- W2393171665 abstract "Objective:To observe the effect of Kudi Shifu Ji(KDSFJ) on the treatment of the established mouse model of allergic contact dermatitis(ACD).Methods:Allergic contact dermatitis mice model were established by DNFB.Successful models were randomly divided into A,B and C groups.Group A were sprayed with KDSFJ and Group B were sprayed with boric acid in 6days.Group C was considered as the blank control group.The effect of KDSFJ on the treatment of the models were evaluated by the relative clinical indexes of observing the change of the skin lesions with naked eyes,measuring the thickness of middle part of bilateral ears with external diameter micrometer and weighting the tissue obtained with a puncher.Results:1.Before or after the model was established,no significant difference of mice weight was found among three groups at the same time.2.No significant difference has manifested between the left and right ear thickness of mice before the models were established(P= 0.195,P= 0.061) or right before the treatment(P= 0.303,P= 0.130).3.On the 12th day of treatment,all the local skin lesions on mice of the study group were scab off,inducing a better effect than the other two groups;4.On the 6th day,swelling of auricle of the left on study group was lighter than that of positive control group and blank control group,but the difference was not statistically significant;5.he scores of skin lesions were significantly different among the three groups on 6th day,suggesting that KDSFJ can effectively reduce the erythema and other lesions.The effect of study group was better than that of the control group.Conclusion:Compared with the control group,the erythema and other local lesions of mice in study group are significantly less than those in the other two control groups,confirming that KDSFJ can inhibit the inflammatory response.The experiment lay a foundation for further study." @default.
- W2393171665 created "2016-06-24" @default.
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- W2393171665 date "2012-01-01" @default.
- W2393171665 modified "2023-09-23" @default.
- W2393171665 title "Effect of Kudi Shifu Ji(KDSFJ) on Skin Lesions of Mice Contact Dermatitis" @default.
- W2393171665 hasPublicationYear "2012" @default.
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