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- W2393196027 abstract "【Objective】This paper studied the effects of p-nitrophenol(PNP)on hepatic histopathology and alanine aminotransferase(ALT)activities in Misgurnus anguillicaudatus.【Method】According to the safe concentration and the minimal non-lethal concentration of PNP to Misgurnus anguillicaudatus obtained from preliminary tests,four mass concentrations of PNP(4.40,5.13,5.98and 6.98mg/L)were set up,respectively,and the hepatic tissue of Misgurnus anguillicaudatus at 7,14,21and 28dwere observed using HE method and ALT activities were determined using Lai's colorimetric method.【Result】The hepatic cells exposed to 6.98mg/L PNP become bubbled,and experienced lysis and nucleus deformation at 14d,and additional karyolysis was observed at 28d.ALT activities exposed to PNP with same concentrations increased significantly except for 6.98mg/L at 28d.However,ALT activities decreased as the increase of exposure concentrations,and ALT activities showed decrease after initially increase compared to CK.【Conclusion】PNP damaged hepatic structure of Misgurnus anguillicaudatus and the damages aggravated as the increase of exposure concentrations.PNP also induced the activity of hepatic ALT,but the induction weakened as the increase of exposure concentrations,and decreased after initial increase." @default.
- W2393196027 created "2016-06-24" @default.
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- W2393196027 date "2013-01-01" @default.
- W2393196027 modified "2023-09-23" @default.
- W2393196027 title "Effects of p-nitrophenol on hepatic tissue structure and ALT activities in Misgurnus anguillicaudatus" @default.
- W2393196027 hasPublicationYear "2013" @default.
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