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- W2393273952 abstract "Objective To investigate the spontaneous mutation rate of HBV YMDD motif and its related factors of CHB patients whom under 20 years old and in immune tolerant phase .Methods To filtrate 110 CHB cases whom under 20 years old and in immune tolerant phase,at the same time these cases do not be treated by any antivirus drugs, then check it YMDD mutations. Rusults Among 110 cases with CHB, spontaneous YMDD variants were detected in 31 cases(YIDD , YVDD and YIDD/YVDD for 9 , 6and 16 cases, respectively).Gender , age , HBeAg status , serum HBV DNA levels and alanine aminotransferase (ALT)levels were not found to be significantly related with spontaneous YMDD mutation.Conclusions Spontaneous YMDD variants exist in patients with CHB (whom under 20 years old and in immune tolerant phase) , and are unrelated with gender , age , HBeAg status , serum viral levels or ALT levels." @default.
- W2393273952 created "2016-06-24" @default.
- W2393273952 creator A5049761910 @default.
- W2393273952 date "2010-01-01" @default.
- W2393273952 modified "2023-09-28" @default.
- W2393273952 title "Epidemiological Survey for Spontaneous HBV YMDD Motif Mutation of CHB Patients whom under 20 Years Old and in Immune Tolerant Phase" @default.
- W2393273952 hasPublicationYear "2010" @default.
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