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- W2393314590 abstract "Objective To research the amount and maturity of dendritic cell (DC) in joint fluid and peripheral blood of ankylosing spondylitis (AS) patients.Methods The dendritic cells from white blood cells (WBC) were selected by setting up the gate in flow cytometer with combined fluorescence antibodied (CD3,CD14,CD16,CD19,CD20,CD56).The amount of CD11c + DC and CD 123 + DC in joint fluid as well as peripheral blood of ankylosing spondylitis patient (n=30) and normal healthy subjects (n=30) were measured simultaneously by flow cytometer.Results The percentage of CD11c+ DC in peripheral blood of AS patients(0.30±0.09%) was more than that in control group (0.18±0.08%) ( t =5.459, P 0.001).The percentage of CD11c+ DC in joint fluid of AS patients(0.45 ±0.11%) was more than that in peripheral blood( t =5.781, P 0.001).There was no difference of percentage of CD123+ DC in peripheral blood between AS patients(0.15 ±0.08%) and control group (0.12±0.07%) ( t =1.546, P 0.05).The percentage of CD123+ DC in joint fluid of AS patients (0.23±0.08%) was more than that in peripheral blood( t =3.874, P 0.001 ).Conclusions Increased DC amount with both high and low maturity was found in joint fluid of AS patients, while only increased DC amount with high maturity was found in peripheral blood of AS patients.Thus,a high level of antigen presentation in AS patients is exhibited and there is a close relationship between DC amount and AS." @default.
- W2393314590 created "2016-06-24" @default.
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- W2393314590 date "2005-01-01" @default.
- W2393314590 modified "2023-09-27" @default.
- W2393314590 title "Change of dendritic cell quantity in joint fluid and peripheral blood of ankylosing spondylitis patients" @default.
- W2393314590 hasPublicationYear "2005" @default.
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