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- W2393326053 abstract "Colorectal cancer represents one of the most common cancers in the wor ld,the incidence and mortality increased in recent years.The pathogenesis is n ot very clear,so the early diagnosis and therapy for advanced cancer are very d ifficult.Genetics and environment are main reasons associated with colorectal c ancer carcinogenesis.Approximately 20% of all colorectal cancer cases are familial inheritance of the disease and the others are sporadic colorectal cance r.The molecular pathways are variable,but three pathways should be paid more attention,in cluding chromosomal instability(CIN),microsatellite instability(MSI) and the CpG i sland methylator phenotypec(CIMP).This review examines the underlying molecula r mechanism,cancer stem cells and colitis-associated cancer in colorectal cancer carcinogenesis." @default.
- W2393326053 created "2016-06-24" @default.
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- W2393326053 date "2011-01-01" @default.
- W2393326053 modified "2023-09-23" @default.
- W2393326053 title "The progress and future directions of colorectal cancer" @default.
- W2393326053 hasPublicationYear "2011" @default.
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