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- W2393349946 abstract "Objective To explore the effect of anti-aging No. 1 on liver mitochondrial DNA(mtDNA) deletion in aged Balb/c mice. Methods The aged Balb/c mice were randomly divided into normal aged control group given physiological saline and aged anti-aging No. 1 group given anti-aging No. 1 for 4 months. The deletions of liver mtDNA in two groups were detected by polymerase chain reaction (PCR) and light density scanning. Results Compared with the aged control group, anti-aging No. 1 could remarkably reduce the mtDNA deletions in liver of the aged Balb/c mice(P 0.001). Conclusions Anti-aging No. 1 could inhibit the increase of mtDNA deletion in aged mice, the prescription for reinforcing kidney and spleen, dredging intestines and accelerating the circulation of blood could decrease mtDNA oxidative damage and protect mtDNA. Thereby it may be responsible for retarding aging at the aspect of molecular pathogenesis." @default.
- W2393349946 created "2016-06-24" @default.
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- W2393349946 date "2005-01-01" @default.
- W2393349946 modified "2023-09-28" @default.
- W2393349946 title "Effect of anti-aging No. 1 on liver mitochondrial DNA deletion in aged Balb/c mice" @default.
- W2393349946 hasPublicationYear "2005" @default.
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