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- W2393375760 abstract "Objective: To explore the effect of autologous dendritic cells(DC) and cytokine induced killer(CIK) cells combined with intravesical instillation of pirarubicin on postoperative recurrence and survival rate for bladder cancer. Methods: One hundred and two patients of bladder cancer who were undergone surgery from June 2009 to June 2012 were divided into control group and observing group. Patients in the control group were treated with intravesical instillation of pirarubicin. After 4 period, cumulative recurrence rate, cumulative survival rate, safety and immunity function(CD3, CD4, CD4/CD8) were analyzed in the control group and observing group. Results: The cumulative recurrence in the observing group significantly decreased than that in the control group(P0.05). The cumulative survival rate in the observing group was significantly increased than that in the control group(P0.05). The side effect was caused by chemotherapy. The main side effect exhibited urinary frequency, urgency and odynuria. CD3, CD4 and CD4/CD8 in the observing group significantly increased than that in the control group(P0.05).Conclusion: DC-CIK cells combined with intravesical instillation of pirarubicin is worth to clinical application for that can reduce postoperative recurrence, prolong the survival time, improve immunity function." @default.
- W2393375760 created "2016-06-24" @default.
- W2393375760 creator A5037798678 @default.
- W2393375760 date "2013-01-01" @default.
- W2393375760 modified "2023-09-27" @default.
- W2393375760 title "Effect of autologous dendritic cells(DC) and cytokine induced killer(CIK) cells combined with intravesical instillation of pirarubicin on postoperative recurrence and survival rate for bladder cancer" @default.
- W2393375760 hasPublicationYear "2013" @default.
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