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- W2393397302 abstract "Objective:To study the correlation of albuminuria and cardiovascular disease (CVD) in the hospitalized patients with chronic kidney disease (CKD) .To evaluate the predictive value of albuminuria on CVD in non-diabetic CKD patients.Methods:1 245 adult CKD patients hospitalized in our renal center without diabetes and renal replacement therapy were retrospectively studied.Clinical characters and risk factors of cardiovascular disease in CKD patients were analyzed.Results:(1) Patients at CKD stage 1,2,3,4,and 5 were 24.4%,22.6%,29.9%,12.6%%,10.5%,respectively.Patients with proteinuria at CKD stage 1,2,3,4,and 5 were 68.8%,69%,72.3%,74.5% and 80.9% respectively.(2)Compared with the CKD1 patients,the ages,SBP,DBP,Scr and UA was increasingly higher in CKD2~5 patients,and eGFR,Hb,Alb was significantly lower (P0.05);TG,LDL were increased and HDL decreased in CKD3,(P0.05);TC,LDL,HDL decreased and TG increased in CKD4,5(P0.05).(3)In the same stage of CKD,compared with non-albuminuria patients,Scr,UA was significantly higher in patients with albuminuria in CKD1~5,and Alb was significantly lower (P0.05);SBP,DBP significantly increased in patients with albuminuria in CKD2~5,and eGFR,Hb was significantly lower (P0.05);TC,HDL decreased in patients with CKD4,5,and TG,LDL increased(P0.05).(4)The prevalence of CVD and abnormalities of chest X-ray,ECG,UCG in CKD was increased from stage 1 to 5 progressively (P0.05).In the same stage of CKD,compared with non-albuminuria patients,incidence of CVD in patients,abnormalities of chest X ray,ECG,echocardiography were significantly higher (P0.05) in CKD2~5 patients with albuminuria.(4)Logistic Regression analysis showed that CVD is positively correlated with age,SBP,UA,TG,negatively correlated with GFR,Hb(P0.05).Conclusion:In non-diabetic CKD patients,the incidence of CVD is increased with the progress of CKD.Incidence of CVD is closely related with albuminuria,and albuminuria is the risk marker of cardiovascular disease in CKD patients." @default.
- W2393397302 created "2016-06-24" @default.
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- W2393397302 date "2011-01-01" @default.
- W2393397302 modified "2023-09-28" @default.
- W2393397302 title "The Relationship Between Albuminuria and Cardiovascular Event in the Hospitalized Patients with Chronic Kidney Disease" @default.
- W2393397302 hasPublicationYear "2011" @default.
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