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- W2393448051 abstract "Objective To extend the value and scope of plasma perfusion using HB-H-6 resin in patients with chronic liver disease and severe jaundice.Methods From October 2006 to July 2010,a total of 94 different causes of chronic liver diseases with severe jaundice were enrolled,male 68,female 26,aged 29-76 years old,median age 57 years old.The blood bilirubin level both before and after treatment were tested and analyzed,and the optimal initial bilirubin ranges and prothrombin time activity(PTA) for HB-H-6 resin therapy were further explored and adverse reactions were recorded.Results The values of total bilirubin(TBiL),direct bilirubin(DBiL) and indirect bilirubin(IBiL) were(387.80 ± 183.08) μmol/L,(238.66 ± 103.52) μmol/L,(127.23 ± 62.00) μmol/L before treatment,and(291.80 ± 135.58) μmol/L,(183.10 ± 76.29) μmol/L,(92.85 ± 54.25) μmol/L after HB-H-6 resin plasma perfusion treatment respectively.The values of TBiL,DBiL and IBiL were decreased significantly after every single therapy(P 0.01);The level of TBiL,DBiL and IBiL eliminated by HB-H-6 resin were 23.68 % ± 9.14 %,21.54 % ± 9.90 %,27.09 % ± 16.84 % respectively;the absorptive ability for IBiL was a little higher than that for TBiL and DBiL(P 0.01).Plasma perfusion with HB-H-6 could effectively decrease different levels of initial TBiL(P 0.01),the higher the initial bilirubin level,the stronger the absolute value(P 0.01).The TBiL elimination ability was significantly higher when serum TBiL was more than 200 μmol/L before HB-H-6 resin plasma perfusion therapy,compared with that less than 200 μmol/L(P 0.01) and the absorptive ability did not changed with original PTA level.Conclusion It is demonstrated that HB-H-6 resin could be used as an artificial liver effectively and safely in chronic liver disease with severe jaundice as well as in the patients whose value of TBiL are more than 200 μmol/L." @default.
- W2393448051 created "2016-06-24" @default.
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- W2393448051 date "2011-01-01" @default.
- W2393448051 modified "2023-09-25" @default.
- W2393448051 title "Clinical scope analysis of plasma perfusion using HB-H-6 resin in patients with chronic liver disease and severe jaundice" @default.
- W2393448051 hasPublicationYear "2011" @default.
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