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- W2393457793 abstract "Objective To observe the effects of bovine colostrum(BC) on the immunological function in immunosuppressive mice.Methods Female ICR mice were randomly assigned into five groups: normal control group(NC),model control group(MC),low,medium,and high dosage BC groups(BL,BM,BH).Four weeks later,spleen and thymus were weighted,cell-mediated immune function,humoral immune function,phagocytic function of mononuclear phagocyte and the T cell subpopulation in spleen were assayed.Results The spleen and thymus index in BL,BM and BH were drastically decreased in comparition with NC(P0.01).The capacities of lymphocyte proliferation induced by ConA in BM and BH were obviously higher than those of MC(P0.01).The numbers of hemolytic plaques in all three BC groups were larger than those of MC(P0.01),yet the values in BL and BH were much smaller than NC(P0.01).All the BC groups' corrected phagocytic coefficient α were drastically higher than MC and NC(P0.01).Lastly,the CD4+ T cell of spleen in BM were greatly higher than MC and NC(P0.01).Conclusion Bovine colostrum was efficaciously increase cellular immune level,antibody forming level and phagocytic function of mononuclear phagocyte and the decrease of CD4+T cell in spleen inhibited by cyclophosphamide." @default.
- W2393457793 created "2016-06-24" @default.
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- W2393457793 date "2009-01-01" @default.
- W2393457793 modified "2023-09-26" @default.
- W2393457793 title "Study of the Effect on The Immunological Function of Bovine Colostrum in Immunosuppressive Mice" @default.
- W2393457793 hasPublicationYear "2009" @default.
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