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- W2393498538 abstract "Objective To explore the expression of CD137 and its biological function on CD4+CD25+ regula-tory T cell(Treg).Methods Anti-CD137 mAb was added to stimulate the T cells that activated by PHA.T cell proliferation was determined by cell counts manually at 2d.The phenotypes was determined by FACS.Results FACS analysis showed that the expression of CD137 was upregulated on the PHA activated T cells.Cell counts showed that anti-CD137 MAb could promote the proliferation of T cell,and FACS revealed that the percentage of Treg in activated T cells and downregulated the expression of CD95.Conclusion CD137 is upregulated and plays inhibitory role on activated treg cells and promotes the proliferation of other T cell subsets." @default.
- W2393498538 created "2016-06-24" @default.
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- W2393498538 date "2007-01-01" @default.
- W2393498538 modified "2023-09-27" @default.
- W2393498538 title "The Expression of CD137 and Its Inhibitory Effects on the Treg Cells" @default.
- W2393498538 hasPublicationYear "2007" @default.
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