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- W2393556561 abstract "Objective To study on the of insulin secretion relations to plasma glucose and the effect of different plasma glucose levels on insulin secretion stimulated by glucose.Methods 98 patients with type 2 diabetes were undergone 75g orally glucose tolerance test(OGTT) and insulin releasing test(IRT) 48hours after stopping administration of oral hypoglycemia agent.The data of plasma levels of glucose and insulin,and the time of peak glucose and insulin and postprandial plasma gluocse and insulin ,the time of peak glucose value,the ratio of maximal glucose to base glucose on base and stimulated insulin secrtion were analyzed statistically.Results The findings demonstrated that plasma glucose of OGTT has relation to base insulin level wihle no significance ,but to stimulate insulin (I max ) of IRT and the ratio of maximal insulin to base insulin(M/B 1).I max and M/B 1 when base glucose level excess 11 1mmol/L were one third of the same index when base glucose level less than 11 1mmol/L(P0 01).I max and M/B 1 are lower significantly when peak glucose level excess 16 7mmol/L as compared with less than 16 7mmol/L(P0 01～0 05);the later comes top glucose value during OGTT,the lower are I max and M/B 1;I max and M/B 1 were higher when the ratio excess 2 as compared with less than 2.Conclusions Hyperglycemia(fasting or postprandial glucose)of type 2 diabetes has considerable destructive effect on stimulated insulin level, but base insulin level." @default.
- W2393556561 created "2016-06-24" @default.
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- W2393556561 date "2002-01-01" @default.
- W2393556561 modified "2023-09-24" @default.
- W2393556561 title "Study on the Relationship Between Plasma Glucose Level and Insulin Secretion in Type 2 Diabetes" @default.
- W2393556561 hasPublicationYear "2002" @default.
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