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- W2393567994 abstract "Objective: Our aim was to investigate the relationship among helicobacter pylori (HP) associated gastric diseases, telomerase activity and gastric cancer. Methods: Telomerase activity was detected by using TRAP ELISA protocol in 94 cases of gastric mucosa biopsy including 10 cases of normal gastric mucosa, 21 of superficial gastritis, 33 of atrophic gastritis, 7 of dysplasia, and 23 of gastric cancer. There were 41 of HP positive cases and 20 of negative cases. Results: There was difference of telomerase activity between atrophic gastritis, dysplasia, gastric cancer, and normal gastric mucosa (P0.05 or P0.01). Expression of telomerase activity in gastric cancer was the highest. Between the HP positive group and the HP negative group of different gastric mucosa, the difference was significant (P0.01). Conclusion: Infection with HP may increase telomerase activity and promote the proliferation of cells. The proliferative characteristics of HP associated gastric diseases are similar to that of gastric cancer." @default.
- W2393567994 created "2016-06-24" @default.
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- W2393567994 date "2002-01-01" @default.
- W2393567994 modified "2023-09-23" @default.
- W2393567994 title "Detection and Analysis on the Expression of Telomerase Activity in Helicobacter Pylori Association Gastric Diseases" @default.
- W2393567994 hasPublicationYear "2002" @default.
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