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- W2393662313 abstract "In recent years,paclitaxel has played a significant role in the treatment of various malignancies.However,intravenous administration of paclitaxel was hindered by poor water solubility.Paclitaxel was dissolved in a mixture of ethanol and Cremophor EL,and this formu1ation was associated with significant side effects in vivo,The efficacy of paclitaxel could be significantly enhanced and the toxicity could be reduced by the common carrier or the modified and reshaping carrier.Also,the modified and the structural modification of paclitaxel could increase its water-soluble and reduce its toxicity.The application status,adverse effects and dosage form of paclitaxel was overviewed in this article." @default.
- W2393662313 created "2016-06-24" @default.
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- W2393662313 date "2010-01-01" @default.
- W2393662313 modified "2023-09-28" @default.
- W2393662313 title "Advances in development of new dosage form of paclitaxel" @default.
- W2393662313 hasPublicationYear "2010" @default.
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