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- W2393670587 abstract "Objective To study the characteristics of hematological malignancies after chemotherapy with fungal sepsis. Methods Clinical data of 180 patients with hematological malignancies who received chemotherapy were retrospectively analyzed. Results Among 180 patients,10 patients had fungal sepsis after chemotherapy,including 7 males and 3 females,the incidence rate was 5. 5%,with a median age of 40. 3 years( 16 to 78 years). There were 4 cases of acute lymphoblastic leukemia,3 acute myeloid leukemia,1 multiple myeloma,1 non-Hodgkin's lymphoma,and 1 hemophagocytic syndrome. Fungal sepsis appeared 7 ~ 32 days after chemotherapy,average time was 17. 9 days. Pathogens were all candida,including 5 cases of candida albicans,2 cases of candida glabrata,2 cases of candida tropicalis and 1 cases of candida parapsilosis. According to the drug sensitivity test, voriconazole( 4 mg / kg,2 / d) antifungal therapy was selected. The average treatment time was 16. 5d( 7 ~ 35 days),8 patients were cured and 2 patients died of lung infection. The total effective rate was 80%. Conclusion Hematologic malignancies can develop fungal sepsis after chemotherapy and major pathogens is candida. The mortality rate is higher and early empirical antifungal therapy should be selected based on drug susceptibility test." @default.
- W2393670587 created "2016-06-24" @default.
- W2393670587 creator A5018062930 @default.
- W2393670587 date "2014-01-01" @default.
- W2393670587 modified "2023-09-26" @default.
- W2393670587 title "Clinical Analysis of Hematological Malignancies after Chemotherapy with Fungal Sepsis" @default.
- W2393670587 hasPublicationYear "2014" @default.
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