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- W2393695498 abstract "Age-related macular degeneration(AMD) is characterized by tardive and progressive.It is marked by some kinds of noninfective injury around macular area and is a major cause of visual disability for people older than 50.Recent researches indicate that the genetic factors play important roles in AMD,and the inherent immune system may affect the pathological process of AMD.Complement factor H can increase the risk of white people suffering from AMD,while the second risk factor is LOC387715/HTRA1 located within the chromosome 10q26 that is just secondary to complement factor H.All these lead to the formation of AMD mainly through promoting changes of retinal pigment epithelium/Bruch membrane and/or the formation of drusen.The researches on gene polymorphisms provide new strategies for treatment.However,the current understanding on gene polymorphisms of AMD stays at foundmental research,the function and mechanisms are not clear and further studies are needed." @default.
- W2393695498 created "2016-06-24" @default.
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- W2393695498 date "2009-01-01" @default.
- W2393695498 modified "2023-09-23" @default.
- W2393695498 title "Current situation and existing problems of gene polymorphisms in age-related macular degeneration" @default.
- W2393695498 hasPublicationYear "2009" @default.
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