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- W2393704893 abstract "Purpose:To explore the renal adaptation under hypoxia environment in which the health youngs were exposed to 2750 m altitude from sea level.Methods:The study on rabbits renal histopathology in which the rabbits were exposed to 2750 m altitude from sea level.450 health youngs were divided into groups A (staying altitude 6 months),group B (staying altitude a year) and group C (sea level).To observe the morphologic change of renal by ultrasonography,blood and urine biochemical and albuminuria radioimmunoassay had been examined.Results:A. Rabbits renal histopathology:angiectasis hyperemia of peritubular capillary and interstitial cell hydropic degeneration of renal tubular epithelial cell.B. Positive rate of urine biochemical:group A and B were all higher than the control group C(P 0.01 ),group A was higher than group B(P 0.01 ).C. The volume of renes of subjects were not changed between groups (P 0.05 ).D. Cr of blood and urine were all abnormal,in group A and B,out of them,group B positive rate was 44.1 %,was higher than group A (P 0.01 ).β 2 MG was abnormal in group A and B.α 1 MG was lower than normal (P 0.01 ) in group A and B. group B was higher than Group A (P 0.01 ).Conclusions:It can be induced early the injury of kidney in healthy young at altitude from sea level.The manifestation is albumnuria.The injury of renal tubular and glomerulus was synchronism,but the morphologic of renes were not changed under hypoxia environment.The injury may be changed more less staying long time at altitude,renes can be toleration and compensation hypoxia at altitude." @default.
- W2393704893 created "2016-06-24" @default.
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- W2393704893 date "2001-01-01" @default.
- W2393704893 modified "2023-09-25" @default.
- W2393704893 title "Research for renal toleration when the organism exposed acutively to high altitude hypoxia environment" @default.
- W2393704893 hasPublicationYear "2001" @default.
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