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- W2393756043 abstract "Objective To explore the clinical and laboratory characteristics of patients with dengue fever (DF) in Guangzhou from May 2002 to November 2003. Methods Clinical data from 1032 patients with DF were retrospectively analyzed. Dengue virus (DEV) were isolated by cell culture and typed by reverse transcriptase polymerase chain reaction (RT-PCR). Results Patients ranged from 55 day to 91 year old [average (34.7±13.2) years]. The common manifestations included fever (100%), headache (90.9%), myalgia (68.4%), bone soreness (48.8%), fatigue (79.3%), skin rash (60.1%), positive tourniquet test (45.3%), leukopenia (63.3%), thrombocytopenia (60.8%), respectively. Other common findings were elevated alanine aminotransferase (71.8%), elevated aspartate aminotransferase (86.9%), elevated lactase dehydrogenase (44.7%), elevated creatinine kinase (31.3%) and hypopotassemia (19.2% ). Only 2 patients were clinically diagnosed as dengue haemorrhagic fever (DHF), the others were all diagnosed as common DF. DEV were isolated from 19 of 54 serum samples of patients within 5 days of the onset and then identified as DEV type Ⅰ. Serum DEV RNA was detected by RT-PCR in 25 of 30 patients(83.3%). Conclusions The epidemic of dengue fever in Guangzhou in recent years were caused by DEV-Ⅰ. Most patients are classic dengue fever but with high percentage of hepatic injury and hypopotassemia. The incidence of DHF was very low." @default.
- W2393756043 created "2016-06-24" @default.
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- W2393756043 date "2005-01-01" @default.
- W2393756043 modified "2023-09-24" @default.
- W2393756043 title "Clinical and laboratory characteristics of 1032 patients with dengue fever in Guangzhou from 2002 to 2003" @default.
- W2393756043 hasPublicationYear "2005" @default.
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