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- W2393761311 abstract "Objective To analyze the clinical effects of early intervention and delayed using the non-invasive ventilation in patients with acute COPD exacerbation.Methods According to the time of giving non-invasive ventilation,all patients with acute COPD exacerbation were divided into the early intervention treatment group(43 cases) and delayed treatment group(40 cases).The delayed treatment group received conventional treatment including administration of oxygen,anti-infection,anti-inflammation,relieve spasm,antiasthmatic and expectorant treatment;after a period of time of treatment,the patients who did not alleviate were given ventilator therapy and some of them required intubation.On the basis of conventional treatment,the early intervention treatment group received non-invasive ventilation therapy early.Breathing difficulties and intoxicated condition,heart rate(HR),respiratory rate(RR) and mean arterial pressure(MBP) were observed after treating 3 hours.Arterial oxygen partial pressure(PaO2) and partial pressure of carbon dioxide(PaCO2) results were obtained before and after mechanical ventilation.At the same time,the improvement rate,hospitalization time and endotracheal intubation rate were observed.The data of the patients before and after therapy were compared.Results Compared with conventional treatment group,HR,RR,MBP,tidal volume,PaO2 and sign improved more obviously in early intervention treatment group(all P 0.05).In addition,higher improvement rate,shorter hospital time and lower endotracheal intubation rate were observed in early intervention treatment group.Conclusion Early application of noninvasive ventilation treatment may rapidly improve the patients' symptoms and hypoxemia,decrease the need for endotracheal intubation in patients with acute exacerbation COPD.And it is a fast,safe and effective rescue measure." @default.
- W2393761311 created "2016-06-24" @default.
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- W2393761311 date "2013-01-01" @default.
- W2393761311 modified "2023-09-26" @default.
- W2393761311 title "The comparative study of early intervention and delayed using the non-invasive ventilation in patients with acute exacerbation of COPD" @default.
- W2393761311 hasPublicationYear "2013" @default.
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