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- W2393787523 abstract "Objective Anti hydatid efficacy for Echinococcus granulosus protoscoleces( Eg PSC) was investigated by using Oxibendazole (OBZ), Albendazole (ABZ) and Liposomal Albendazole (L ABZ) in vitro . Methods Eg PSC was cultured in three drugs concentrations 2 500 ng/ml, 500 ng/ml, 100 ng/ml) of OBZ, ABZ and L ABZ in the RPMI1640 culture media respectively. The mortality in each group was daily counted until 100% Eg PSC death in control. Results Significant difference of Eg PSC mortality was found among these three drugs with various concentrations compared to control group ( P 0.05); In L ABZ group, however the statistical difference was found only in high concentrations( P 0.05). Conclusion The significant anti protoscolece effect for these three drugs was found in our current experiment in vitro . OBZ had the similar anti hydatid effect compared with ABZ in vitro , which could be considered as a potential candidate drug against E. granulosus . L ABZ did not demonstrate the significant effect of anti hydatid Eg PSC in vitro ." @default.
- W2393787523 created "2016-06-24" @default.
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- W2393787523 date "2002-01-01" @default.
- W2393787523 modified "2023-09-25" @default.
- W2393787523 title "COMPARATIVE STUDY ON THREE DRUGS AGAINST ECHINOCOCCUS GRANULOSUS PROTOSCOLECES IN VITRO" @default.
- W2393787523 hasPublicationYear "2002" @default.
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