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- W2393800510 abstract "Objective TO develop a biodegradable drug controlled-release system to improve theconcentration of chemotherapeutant in brain glioma and reduce its toxicity. Methods Adriamycin-PLA was made by mixingthem in a certain proportion. Its releasing rate was detected with HPLC. The biocompatibility, cell toxicity,chemotherapeutic effect and side effects was tested in rat glioma model. Results The C6 glioma in rats model was eliminated in 7 days with slight bone marrow depression. The Adriamycin-PLA has not caused inflammatory reaction.Conclusions Adr-PLA controlled-releasing system has a good killing effection ac glioma in rat, good biocompatibility, with slight side effects." @default.
- W2393800510 created "2016-06-24" @default.
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- W2393800510 date "1999-01-01" @default.
- W2393800510 modified "2023-09-25" @default.
- W2393800510 title "Interstitial chemotheyrapy with biodegradable Adriamycin-PLA polymer for C6 glioma model in rats" @default.
- W2393800510 hasPublicationYear "1999" @default.
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