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- W2393819899 abstract "Objective To analyze the adverse reaction of severe hypotension and rise of tracheal pressure due to Protamine combined with heparin in heart surgery and clinical emergency treatment.Methods To analyze retrospectively 47 severe ADR cases of Protamine from 2009 to 2010 in Jinan.38 patients were caused moderate or severe hypertension(blood pressure decreased by 30～≥50mmHg) after Protamine injection,9 patients were caused slight hypertension(blood pressure decreased by 20～29mmHg).Results After emergency treatment and blood transfusion,40 cases returned to normal blood pressure in 5min,85.11% in 47 patients.While 7 patients had been improved in 10～30min through extracorporeal circulation rebuilt and manually controlled respiration besides of the medicine treatment.Conclusion Protamine may cause severe hypotension.In surgery,the preventive measures and active treatment is the key to lower the occurring rate of severe ADR." @default.
- W2393819899 created "2016-06-24" @default.
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- W2393819899 date "2011-01-01" @default.
- W2393819899 modified "2023-09-23" @default.
- W2393819899 title "Analysis of 47 ADR Cases of Severe Hypotension Induced by Protamine" @default.
- W2393819899 hasPublicationYear "2011" @default.
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