Matches in SemOpenAlex for { <https://semopenalex.org/work/W2393828195> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W2393828195 abstract "Objective:To observe the level of endogenous cortisol in patients with advanced gastrointestinal cancer,and to evaluate the effect of exogenous glucocorticoids treatment on patient's malignant symptoms and serum cortisol level.Methods:Thirty-one patients with advanced gastrointestinal cancer who were given 40 mg/d methylprednisolone for continuous 5 days.The patients included 8 patients with esophageal and cardial cancer,12 patients with gastric cancer,and 11 patients with colorectal cancer.At the same time,30 healthy adults were selected as control group.The cortisol radioactive immunoassay kit was used to determine the level of serum cortisol in the gastrointestinal cancer patients and controls.The life quality changes of gastrointestinal cancer patients were evaluated.Results:The serum cortisol level of 31 advanced gastrointestinal cancer patients was higher than that of healthy volunteers [(312.39±57.64)vs(144.64±52.20) μg/L,P0.01].The average serum cortisol levels in the patients with esophageal cancer,gastric cancer and colorectal cancer were higher than healthy controls(P0.05).The serum cortisol level in gastric cancer patients was the highest among the three types of gastrointestinal cancers(P0.01).After being treated with exogenous glucocorticoids,the five parameters such as appetite,spirit,sleeping,fatigue and pain in gastrointestinal cancer patients were improved significantly.During the course of exogenous glucocorticoid treatment,there were no serious complications.The serum cortisol levels after exogenous glucocorticoid treatment did not change significantly in the patients with esophageal cancer,gastric cancer and colorectal cancer(P0.05).Conclusion:Endogenous serum cortisol levels of gastrointestinal cancer patients were significantly higher than those of healthy adults.Short-term treatment with medium dosage of exogenous glucocorticoids had little effect on the endogenous serum cortisol level." @default.
- W2393828195 created "2016-06-24" @default.
- W2393828195 creator A5065817915 @default.
- W2393828195 date "2009-01-01" @default.
- W2393828195 modified "2023-09-27" @default.
- W2393828195 title "Effect of glucocorticoids on the level of endogenous cortisol in patients with advanced gastrointestinal cancer" @default.
- W2393828195 hasPublicationYear "2009" @default.
- W2393828195 type Work @default.
- W2393828195 sameAs 2393828195 @default.
- W2393828195 citedByCount "0" @default.
- W2393828195 crossrefType "journal-article" @default.
- W2393828195 hasAuthorship W2393828195A5065817915 @default.
- W2393828195 hasConcept C121608353 @default.
- W2393828195 hasConcept C126322002 @default.
- W2393828195 hasConcept C134018914 @default.
- W2393828195 hasConcept C2779742542 @default.
- W2393828195 hasConcept C2780841215 @default.
- W2393828195 hasConcept C526805850 @default.
- W2393828195 hasConcept C542804219 @default.
- W2393828195 hasConcept C71924100 @default.
- W2393828195 hasConcept C90924648 @default.
- W2393828195 hasConceptScore W2393828195C121608353 @default.
- W2393828195 hasConceptScore W2393828195C126322002 @default.
- W2393828195 hasConceptScore W2393828195C134018914 @default.
- W2393828195 hasConceptScore W2393828195C2779742542 @default.
- W2393828195 hasConceptScore W2393828195C2780841215 @default.
- W2393828195 hasConceptScore W2393828195C526805850 @default.
- W2393828195 hasConceptScore W2393828195C542804219 @default.
- W2393828195 hasConceptScore W2393828195C71924100 @default.
- W2393828195 hasConceptScore W2393828195C90924648 @default.
- W2393828195 hasLocation W23938281951 @default.
- W2393828195 hasOpenAccess W2393828195 @default.
- W2393828195 hasPrimaryLocation W23938281951 @default.
- W2393828195 hasRelatedWork W1966250003 @default.
- W2393828195 hasRelatedWork W1973625092 @default.
- W2393828195 hasRelatedWork W2011482638 @default.
- W2393828195 hasRelatedWork W2022182994 @default.
- W2393828195 hasRelatedWork W2041881532 @default.
- W2393828195 hasRelatedWork W2061522872 @default.
- W2393828195 hasRelatedWork W2333385737 @default.
- W2393828195 hasRelatedWork W2365806328 @default.
- W2393828195 hasRelatedWork W2375240523 @default.
- W2393828195 hasRelatedWork W2387297819 @default.
- W2393828195 hasRelatedWork W2397338328 @default.
- W2393828195 hasRelatedWork W2401324867 @default.
- W2393828195 hasRelatedWork W2409924158 @default.
- W2393828195 hasRelatedWork W2412432815 @default.
- W2393828195 hasRelatedWork W2415991153 @default.
- W2393828195 hasRelatedWork W2433794172 @default.
- W2393828195 hasRelatedWork W2443921612 @default.
- W2393828195 hasRelatedWork W2754092629 @default.
- W2393828195 hasRelatedWork W2760009289 @default.
- W2393828195 hasRelatedWork W3030011914 @default.
- W2393828195 isParatext "false" @default.
- W2393828195 isRetracted "false" @default.
- W2393828195 magId "2393828195" @default.
- W2393828195 workType "article" @default.