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- W2393862562 abstract "Objective To evaluate the hemodynamic changes induced by different concentration of epinephrinelidocaine solution during craniotomy.Methods Eighty patients accepted craniotomy between May and October 2010.They were randomly divided into four groups.Each group of patients were infiltrated with 16mL of 1% lidocaine solution and different concentrations of epinephrine.Group A accepted 2.5 μg/mL epinephrine,group B 5.0 μg/mL,group C 7.5 μg/mL,and group D 10.0 μg/mL.We recorded the heart rate(HR),mean arterial pressure(MAP),systolic pressure(SBP),diastolic pressure(DBP) at the point of before using epinephrine(T0) and every 30 seconds in 5 min after using epinephrine(T1-10).Based on the lowest and the highest MAP,the reducing and the rising rate of MAP were calculated.Moreover,we calculated the number of patients whose MAP decreased by less than 10%,between 10% and 20%,and beyond 20% on the basis of T0 in all groups.Results MAP falling rate and number of patients with decreased MAP in group C were significantly more than other groups.MAP and SBP falling at minute 1.5,2.0 and 2.5 after using epinephrine,DBP falling at minute 2.0 in group C,MAP and DBP falling at minute 1.5 and 2.0,were significantly different.The arterial pressure dropped with HR accelerating in all groups.However,HR had no significant difference among the groups.Conclusion Low concentration of epinephrine combined with lidocaine solution used for scalp infiltration can cause the patients’ arterial pressure to decrease in craniotomy." @default.
- W2393862562 created "2016-06-24" @default.
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- W2393862562 date "2012-01-01" @default.
- W2393862562 modified "2023-09-23" @default.
- W2393862562 title "Hemodynamics Responses to Epinephrine and Lidocaine in Craniotomy Patients" @default.
- W2393862562 hasPublicationYear "2012" @default.
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