Matches in SemOpenAlex for { <https://semopenalex.org/work/W2393864105> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2393864105 abstract "Objective To observe the effect of ischemic postconditioning on myocyte apoptosis in hyperlipemia rats with myocardial ischemic reperfusion.Methods Total forty-eight hyperlipemia SD rats were randomly divided into the sham-operation group, ischemic reperfusion group and ischemic postconditioning group with 16 rats in each group. The myocardial ischemic reperfusion model of rat was made. Rats in the ischemic reperfusion group were ligated for 40 min ischemia, and then reperfused for 240 min. Rats in the ischemic postconditioning group were treated for 40 min ischemia, reperfused for 10 s and 10 s ischemia for three cycles, and then reperfused for 240 min. Rats in the sham-operation group were opened the chest to braid for ringer without deligation. The presence of apoptotic myocytes was detected by the method of terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling (TUNEL). Meanwhile, the serum creatine kinase activity and myocardial infarct size were measured.Results The creatine kinase activity was 734.86±25.48 U/L in the ischemic postconditioning group and 967.64±28.16 U/L in the ischemic reperfusion group after reperfusion, all significantly higher than that (274.28±16.94 U/L) in the sham-operation group ( P0.05), and it was significantly lower in the ischemic postconditioning group than that in the ischemic reperfusion group ( P0.05). There was no significant difference in ratio of myocardial ischemic size and left ventricle after reperfusion between the ischemic postconditioning group and the ischemic reperfusion group. But the ratio of myocardial necrotic size and ischemic size of the ischemic postconditioning group was 24.8%±6.7% and significantly lower than that (38.2%±7.1%) of the ischemic reperfusion group ( P0.05). No apoptotic myocardial cells were found after the reperfusion in the sham-operation group. The apoptotic rate in the ischemic postconditioning group (12.7%±2.8%) was significantly lower than that (20.9%±3.7%) in the ischemic reperfusion group ( P0.05).Conclusion Ischemic postconditioning can relieve the ischemic reperfusion injury in hyperlipemia rats, the mechanism of which may be related with decreased myocardial apoptosis." @default.
- W2393864105 created "2016-06-24" @default.
- W2393864105 creator A5087780082 @default.
- W2393864105 date "2009-01-01" @default.
- W2393864105 modified "2023-09-24" @default.
- W2393864105 title "Effect of Ischemic Postconditioning on Apoptotic Myocardial Cells in Hyperlipemia Rats with Ischemic Reperfusion" @default.
- W2393864105 hasPublicationYear "2009" @default.
- W2393864105 type Work @default.
- W2393864105 sameAs 2393864105 @default.
- W2393864105 citedByCount "0" @default.
- W2393864105 crossrefType "journal-article" @default.
- W2393864105 hasAuthorship W2393864105A5087780082 @default.
- W2393864105 hasConcept C126322002 @default.
- W2393864105 hasConcept C164705383 @default.
- W2393864105 hasConcept C185592680 @default.
- W2393864105 hasConcept C190283241 @default.
- W2393864105 hasConcept C196795494 @default.
- W2393864105 hasConcept C204232928 @default.
- W2393864105 hasConcept C2778921608 @default.
- W2393864105 hasConcept C2779311647 @default.
- W2393864105 hasConcept C2779896295 @default.
- W2393864105 hasConcept C2780114680 @default.
- W2393864105 hasConcept C2908780116 @default.
- W2393864105 hasConcept C36880943 @default.
- W2393864105 hasConcept C42219234 @default.
- W2393864105 hasConcept C500558357 @default.
- W2393864105 hasConcept C541997718 @default.
- W2393864105 hasConcept C55493867 @default.
- W2393864105 hasConcept C71924100 @default.
- W2393864105 hasConceptScore W2393864105C126322002 @default.
- W2393864105 hasConceptScore W2393864105C164705383 @default.
- W2393864105 hasConceptScore W2393864105C185592680 @default.
- W2393864105 hasConceptScore W2393864105C190283241 @default.
- W2393864105 hasConceptScore W2393864105C196795494 @default.
- W2393864105 hasConceptScore W2393864105C204232928 @default.
- W2393864105 hasConceptScore W2393864105C2778921608 @default.
- W2393864105 hasConceptScore W2393864105C2779311647 @default.
- W2393864105 hasConceptScore W2393864105C2779896295 @default.
- W2393864105 hasConceptScore W2393864105C2780114680 @default.
- W2393864105 hasConceptScore W2393864105C2908780116 @default.
- W2393864105 hasConceptScore W2393864105C36880943 @default.
- W2393864105 hasConceptScore W2393864105C42219234 @default.
- W2393864105 hasConceptScore W2393864105C500558357 @default.
- W2393864105 hasConceptScore W2393864105C541997718 @default.
- W2393864105 hasConceptScore W2393864105C55493867 @default.
- W2393864105 hasConceptScore W2393864105C71924100 @default.
- W2393864105 hasLocation W23938641051 @default.
- W2393864105 hasOpenAccess W2393864105 @default.
- W2393864105 hasPrimaryLocation W23938641051 @default.
- W2393864105 hasRelatedWork W1610503525 @default.
- W2393864105 hasRelatedWork W2026765087 @default.
- W2393864105 hasRelatedWork W2347655256 @default.
- W2393864105 hasRelatedWork W2351120508 @default.
- W2393864105 hasRelatedWork W2354366172 @default.
- W2393864105 hasRelatedWork W2354501778 @default.
- W2393864105 hasRelatedWork W2357818375 @default.
- W2393864105 hasRelatedWork W2360771734 @default.
- W2393864105 hasRelatedWork W2362074272 @default.
- W2393864105 hasRelatedWork W2362850923 @default.
- W2393864105 hasRelatedWork W2363931219 @default.
- W2393864105 hasRelatedWork W2365696302 @default.
- W2393864105 hasRelatedWork W2366008317 @default.
- W2393864105 hasRelatedWork W2366063889 @default.
- W2393864105 hasRelatedWork W2375197821 @default.
- W2393864105 hasRelatedWork W2376591928 @default.
- W2393864105 hasRelatedWork W2380072664 @default.
- W2393864105 hasRelatedWork W2389904000 @default.
- W2393864105 hasRelatedWork W2513184801 @default.
- W2393864105 hasRelatedWork W3030669585 @default.
- W2393864105 isParatext "false" @default.
- W2393864105 isRetracted "false" @default.
- W2393864105 magId "2393864105" @default.
- W2393864105 workType "article" @default.