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- W2393868401 abstract "Objective To study the functional state of platelet and the variation of tissue factor pathway inhibitor (TFPI) in the patients with ulcerative colitis (UC).Methods Platelet aggregability (PAg) was detected by TYXN-91 intelligent blood aggregation and coagulation tester;P-selectin (Ps) was determined with ELISA and TFPI consistency was determined with chromogenic peptide substrate method in 47 patients with UC and 30 healthy controls.Results Increased PAg was detected in active UC compared with inactive UC and healthy controls(P0.01).The levels of Ps and TFPI in the patients with UC were significant higher than those in the controls(P0.01 and P0.05).There was a positive correlation between PAg and TFPI(γ=0.623,P0.01),but there was not correlation between Ps and TFPI(γ= 0.235, P0.05).Conclusions Active UC is marked by increased platelet activation.The platelet activity was also increased in inactive UC.TFPI was increased in the patients with UC,PAg and TFPI play synergetic role in the prothrombotic state of the patients with UC." @default.
- W2393868401 created "2016-06-24" @default.
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- W2393868401 date "2004-01-01" @default.
- W2393868401 modified "2023-09-28" @default.
- W2393868401 title "The functional state of platelet and tissue factor pathway inhibitor in the patients with ulcerative colitis" @default.
- W2393868401 hasPublicationYear "2004" @default.
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