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- W2393910401 abstract "To observe the effect of human augmenter of liver regeneration (hALR) on IL-10 secretion,PBMCs were isolated from healthy volunteers by gradient centrifugation and divided into normal,ALR,ConA and ALR+ConA groups. The proliferation of PBMCs and the levels of IL-2 and IL-10 in the supernatant were detected by MTT and Double-antibody Sandwich Enzyme-linked Immunosorbent Assay respectively when cells were cultured for 16 hours. Correlation between IL-2 and IL-10 was analyzed. As a result,ALR promoted the PBMCs to secret cytokine IL-10,while inhibited the secretion of the cytokines IL-2 and significantly inhibited the ConA positive effect on cell proliferation. In a conclusion,hALR plays immunosuppressive effects possibly through promoting IL-10 secret and inhibiting IL-2 secretion." @default.
- W2393910401 created "2016-06-24" @default.
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- W2393910401 date "2010-01-01" @default.
- W2393910401 modified "2023-09-23" @default.
- W2393910401 title "Effects of human augmenter of liver regeneration on IL-10 secretion" @default.
- W2393910401 hasPublicationYear "2010" @default.
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