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- W2393916360 abstract "Objective To investigate the relationship among HbAlc,blood platelet parameters and fibrinogen connection.Methods 155 patients with DDM and 80 healthy people were enrolled in the study.HbAlc,blood platelet parameters including platelet count,mean platelet volume(MPV) and platelet distribution width(PDW),and fibrinogen(Fbg) were determined for all subjects.According to the HbAlc level and microvascular changes,155 DDM patients were divided into three groups: group A(HbAlc6.0%,complicated with microvascular changes),group B(HbAlc6.0%,without microvascular changes) and group C(HbAlc≤6.0%,keeping a relatively steady blood glucose level,without microvascular changes).The results of platelet parameters and Fbg were compared and statistically analyzed between three disease groups and healthy control group.Results The differences of multiple parameters were statistically significant between group A,B and healthy control group(P0.01).On the contrary,there was no significant differences of multiple parameters between group C and healthy control group(P0.05).Conclusion The microvascular sensitive parameters(MPV,PDW and Fbg) are correlated with HbAlc.For DDM patients with a elevated HbAlc level,their microvascular sensitive parameters have changed,whether there are clinical signs or not.It suggests that platelet parameters and Fbg should be monitored periodically,so as to rectify vascular or microvascular changes complicated with DDM." @default.
- W2393916360 created "2016-06-24" @default.
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- W2393916360 date "2008-01-01" @default.
- W2393916360 modified "2023-09-23" @default.
- W2393916360 title "Relationship among HbAlc,blood platelet parameters and fibrinogen" @default.
- W2393916360 hasPublicationYear "2008" @default.
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