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- W2393936101 abstract "Objective:To verify the in situ apoptotic cell situation on bone marrow biopsy section in patients with myelodysplastic syndrome (MDS).Method:Apoptosis cell were detected in 33 MDS cases by DNA in situ end labelling (ISEL) with 15 cases of iron deficiency anemias (IDA) as control.Apoptotic cells source were defined by morphologic analysis of ISEL positive cells under light microscopy.Result:Mean apoptotic cell number in MDS group is 38.06 ± 24.61 /mm 2,with a mean apoptotic number of 19.20 ± 7.98 /mm 2 in control group (P 0.01 ).RA/RAS subtype of MDS had a higher apoptosis ratio ( 43.58 ± 39.40 /mm 2) than that in RAEB/RAEB T subtype group ( 26.04 ± 21.02 )(P 0.01 ).Apoptosis in granulocyte,erythroid cell and megakaryocyte occupied 38.45 %, 27.33 %, 7.87 % of total apoptotic cells respectively.Conclusion:Overapoptosis is existed in MDS;RA/RAS group had a higher apoptosis ratio than RAEB/RAEB T group;Apoptotic cells derive mainly from granulocytic,erythroid and megakaryocytic hematopoietic lines." @default.
- W2393936101 created "2016-06-24" @default.
- W2393936101 creator A5024203788 @default.
- W2393936101 date "2001-01-01" @default.
- W2393936101 modified "2023-09-25" @default.
- W2393936101 title "Primary study about hematopoietic cell apoptosis on bone marrow sections in patients with myelodysplastic syndrome" @default.
- W2393936101 hasPublicationYear "2001" @default.
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