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- W2393937529 abstract "Objective:To observe the expression of ADRP gene mRNA in fatty tissue of type 2 diabetes Mellitus Rats(T2DM) and discuss the function of ADRP in T2DM nosogenesis.Methods:Ten Wistar Rats were chosen randomly as normal control group of twenty rats,the other ten rats were fed with high glucose and fat diet and injected with small dose of streptozocin(STZ)25mg/kg to be assigned to T2DM model group,after six weeks,the tissue was taken out in empty stomach,we observed insulin through radio-immunity method,calculated ISI and determined FFA.ADRP gene mRNA expression in fatty tissue was determined through RT-PCR.Results:ADRP gene mRNA expression increased obviously in fatty tissue of T2DM,Glucose,Insulin,FFA increased,ISI decreased in empty stomach.Conclusion:Expression of ADRP gene mRNA play an important role in insulin resistance and hypofuntion of β cell." @default.
- W2393937529 created "2016-06-24" @default.
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- W2393937529 date "2008-01-01" @default.
- W2393937529 modified "2023-09-23" @default.
- W2393937529 title "Expression and signification of ADRP gene in fatty tissue of type 2 diabetes mellitus rats." @default.
- W2393937529 hasPublicationYear "2008" @default.
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