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- W2393996646 abstract "Objective To detect the expression of human telomerase RNA(hTR) in adenoid cystic carcinoma(ACC) of salivary glands and to evaluate the relationship between hTR activity and PCNA expression.Methods Nineteen cases of ACC and 4 normal salivary glands were investigated by using in situ-mRNA hybridization(ISH) and immunohistochemical technique.Results Measured by HPIAS-1000 image analysis system,hTR expression was found significantly increased in ACC compared with normal salivary glands(P 0.001 ). HTR levels were significantly different among ACC phenotypes(P 0.05 ).The statistic analyses showed that there were some correlations between hTR and PCNA expression.Conclusion hTR may play a crucial role in the tumorigenesis and progress of ACC,it may be an early event in malignancy." @default.
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- W2393996646 date "2004-01-01" @default.
- W2393996646 modified "2023-09-27" @default.
- W2393996646 title "Human telomerase RNA expression in adenoid cystic carcinoma of salivary gland" @default.
- W2393996646 hasPublicationYear "2004" @default.
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