Matches in SemOpenAlex for { <https://semopenalex.org/work/W2394064139> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2394064139 abstract "In order to study the effect of drug resistance on the radiosensitivity of human ovarian cancer lines exposed to 60Co γ-rays at low absorbed doses, the human ovarian cancer cell line A2780 and its paclitaxel (PTX)-resistant subline A2780/Taxol were used as a model of the cells. MTT assay was used to determine the sensi-tivity of the cells to paclitaxel and radiation. Radioresistance of cells was calculated by colony formation test. The real time PCR was used to determine the variation in the expression of mRNA of MDR1 in the model cells before and after radiation. It has been found that the resistance index (RI) of A2780/Taxol cells is up to 43.96, while the relative survival rate of A2780 cells is more significant than that of 2780/Taxol cells with increment of radiation absorbed dose (p0.05). The results indicate that the PTX-resistant cell line A2780/Taxol has significant radio-resistance. Drug and irradiation can induce over expression of MDR1, which may be one of the main reasons of crossed resistance to chemotherapy and radiotherapy in human ovarian cancer." @default.
- W2394064139 created "2016-06-24" @default.
- W2394064139 creator A5076021322 @default.
- W2394064139 date "2009-01-01" @default.
- W2394064139 modified "2023-09-25" @default.
- W2394064139 title "Studies on radiosensitivity of human ovarian cancer paclitaxel-resistant subline" @default.
- W2394064139 hasPublicationYear "2009" @default.
- W2394064139 type Work @default.
- W2394064139 sameAs 2394064139 @default.
- W2394064139 citedByCount "0" @default.
- W2394064139 crossrefType "journal-article" @default.
- W2394064139 hasAuthorship W2394064139A5076021322 @default.
- W2394064139 hasConcept C111337013 @default.
- W2394064139 hasConcept C114851261 @default.
- W2394064139 hasConcept C121332964 @default.
- W2394064139 hasConcept C121608353 @default.
- W2394064139 hasConcept C126322002 @default.
- W2394064139 hasConcept C185544564 @default.
- W2394064139 hasConcept C187069183 @default.
- W2394064139 hasConcept C206684579 @default.
- W2394064139 hasConcept C2777292972 @default.
- W2394064139 hasConcept C2780427987 @default.
- W2394064139 hasConcept C502942594 @default.
- W2394064139 hasConcept C509974204 @default.
- W2394064139 hasConcept C54355233 @default.
- W2394064139 hasConcept C58962609 @default.
- W2394064139 hasConcept C71924100 @default.
- W2394064139 hasConcept C81885089 @default.
- W2394064139 hasConcept C86803240 @default.
- W2394064139 hasConcept C96232424 @default.
- W2394064139 hasConceptScore W2394064139C111337013 @default.
- W2394064139 hasConceptScore W2394064139C114851261 @default.
- W2394064139 hasConceptScore W2394064139C121332964 @default.
- W2394064139 hasConceptScore W2394064139C121608353 @default.
- W2394064139 hasConceptScore W2394064139C126322002 @default.
- W2394064139 hasConceptScore W2394064139C185544564 @default.
- W2394064139 hasConceptScore W2394064139C187069183 @default.
- W2394064139 hasConceptScore W2394064139C206684579 @default.
- W2394064139 hasConceptScore W2394064139C2777292972 @default.
- W2394064139 hasConceptScore W2394064139C2780427987 @default.
- W2394064139 hasConceptScore W2394064139C502942594 @default.
- W2394064139 hasConceptScore W2394064139C509974204 @default.
- W2394064139 hasConceptScore W2394064139C54355233 @default.
- W2394064139 hasConceptScore W2394064139C58962609 @default.
- W2394064139 hasConceptScore W2394064139C71924100 @default.
- W2394064139 hasConceptScore W2394064139C81885089 @default.
- W2394064139 hasConceptScore W2394064139C86803240 @default.
- W2394064139 hasConceptScore W2394064139C96232424 @default.
- W2394064139 hasLocation W23940641391 @default.
- W2394064139 hasOpenAccess W2394064139 @default.
- W2394064139 hasPrimaryLocation W23940641391 @default.
- W2394064139 hasRelatedWork W1964739617 @default.
- W2394064139 hasRelatedWork W1986475825 @default.
- W2394064139 hasRelatedWork W2003594160 @default.
- W2394064139 hasRelatedWork W2008318438 @default.
- W2394064139 hasRelatedWork W2029128019 @default.
- W2394064139 hasRelatedWork W2041922383 @default.
- W2394064139 hasRelatedWork W2057909786 @default.
- W2394064139 hasRelatedWork W2091914556 @default.
- W2394064139 hasRelatedWork W2352745001 @default.
- W2394064139 hasRelatedWork W2358545775 @default.
- W2394064139 hasRelatedWork W2359623028 @default.
- W2394064139 hasRelatedWork W2360371393 @default.
- W2394064139 hasRelatedWork W2363193798 @default.
- W2394064139 hasRelatedWork W2377563952 @default.
- W2394064139 hasRelatedWork W2382749677 @default.
- W2394064139 hasRelatedWork W2386161697 @default.
- W2394064139 hasRelatedWork W2388043613 @default.
- W2394064139 hasRelatedWork W2403043907 @default.
- W2394064139 hasRelatedWork W2430418298 @default.
- W2394064139 hasRelatedWork W2562411539 @default.
- W2394064139 isParatext "false" @default.
- W2394064139 isRetracted "false" @default.
- W2394064139 magId "2394064139" @default.
- W2394064139 workType "article" @default.