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- W2394134920 abstract "Objective:To investigate the expression of Survivin and its relationship with the clinical features of gallbladder cance r. Methods:45 cases of gallbladder cancer,20 cases of chronic cho lecystitis,20 cases of polypoid lesions of gallbladder (PLG) and 10 cases of no rmal gallbladder tissues were studied, the expression of Survivin was detected b y immunohistochemisty assay. Results:Of the 45 cases of gallbladder cancer,Survivin was expr essed in 40 cases(88.9%).Survivin was not detected in chronic cholecystitis,PLG and normal gallbladder tissues.The expression of Survivin in gallbladder cancer had no association with the patient’s age and gender, tumor size, pathological grading,clinical stage and lymph node metastasis of gallbladder cancer(P 0.05). Conclusion:The excessive expression of Survivin in gallbladder cancer indicates that Survivin could be not only correlated with the occurrence of carcinoma but an early and common event in gallbladder carcinogenesis. Surviv in will promisingly become a novel tumor marker and can be applied in the clinic al practice for helping the early diagnosis as well as targeting gene therapy fo r gallbladder cancer." @default.
- W2394134920 created "2016-06-24" @default.
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- W2394134920 date "2005-01-01" @default.
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- W2394134920 title "Expression and implication of survivin in gallbladder cancer" @default.
- W2394134920 hasPublicationYear "2005" @default.
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