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- W2394193271 abstract "Objective:To study Tiaomian Ⅰ Combining ursodeoxycholic acid's effect of treating autoimmune hepatitis(AIH)through the clinic observation.Methods:Using single-blinded method,60 cases diagnosed as AIH were randomly divided into 2 groups,45 patients were treated with Tiaomian Ⅰ combining ursodeoxycholic acid for 12 months,while the controlled received the treatment of prednisolone(Pred)and azathioprine(AZA).The patients' symptoms and signs,liver function,γ-globulin as well as serum IgG were observed before and after treatment.Results:After 6 or 12 months' treatment observation group could effectively improve the patients' symptoms and signs,and indicated the same effects to liver function,γ-globulin and IgG.Comparing with the controlled combining treatment has better impact on improving patients' debilitation,dry mouth,menstrual disorder and red tongue(P0.05 or P0.01),but the other results had no significant differences(P0.05).The 6 month total effective rate of observation group was 75.6%,which had no significant difference with the controlled 73.3%(P0.05).After 12 month,the results reach 77.8% and 80.0%.They also had the similar effect(P0.05).Conclusion:Tiaomian Ⅰ combining ursodeoxycholic acid is a kind of effective medicine to treat the AIH patients with insufficiency of liver and kidney,and blood stasis.It has the comparable effect with the standard treatment of Pred combining AZA,and hold an advantage of bettering complains and physical signs,and avoiding Pred's side effects." @default.
- W2394193271 created "2016-06-24" @default.
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- W2394193271 date "2009-01-01" @default.
- W2394193271 modified "2023-09-25" @default.
- W2394193271 title "Clinic observation of 45 cases of autoimmune hepatitis treated by Tiaomian I combining ursodeoxycholic acid" @default.
- W2394193271 hasPublicationYear "2009" @default.
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