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- W2394208367 abstract "Purpose To investigate the expression of Ezrin,a membrane-cytoskeleton linker and regulator of cellular signaling,is associated with clinical features of chondrosarcoma.Methods The expression of Ezrin protein was detected by immunohistochemistry method in 42 cases of chondrosarcoma and 20 cases of chondroma.Results(1)The positive rates of Ezrin protein were 61.90% in chondrosarcoma which is higher than that in the cases of chondroma(25.00%),the difference has statistical significance(P0.05).(2)The positive rates of Ezrin protein were 60.61%、50%、71.43% in conventional chondrosarcoma,clear cell chondrosarcoma and dedifferent chondrosarcoma.(3) The positive rates of Ezrin protein were 25%、64.29%、81.82% in grade Ⅰ-Ⅲ of conventional chondrosarcoma,the difference has statistical significance(P0.05).Conclusions High Ezrin protein expression may be correlates with aggressive and metastasis of chondrosarcoma.Ezrin protein detection may be as a tool for differentiate chondrosarcoma with chondroma with active proliferation." @default.
- W2394208367 created "2016-06-24" @default.
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- W2394208367 date "2011-01-01" @default.
- W2394208367 modified "2023-09-24" @default.
- W2394208367 title "Expression of ezrin and its clinical significance in chondrosarcoma" @default.
- W2394208367 hasPublicationYear "2011" @default.
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