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- W2394224583 abstract "OBJECTIVE: To investigate the expression of midkine(MK) and microvessel density(MVD) in non-small cell lung cancer(NSCLC) and the relation of midkine to NSCLC,biological feature,angiogenesis and prognosis.METHODS:The expression of MK and MVD which was marked by CD34 were detected by SP immunohistochemical technique in 60 samples of NSCLC and 10 subjects of paracancerous tissues.RESULTS:MK expressed in tissues of NSCLC but not in the paracancerous tissues.The expression of MK in NSCLC were correlated with TNM stage and lymph node metastasis,P0.05.The expression of MK in NSCLC were not correlated with the histological type,differentiation,sex and age,P0.05.MVD in NSCLC was significantly higher than that in paracancerous tissues,being correlated with TNM stage and lymph node metastasis,P0.05.MVD was not correlated with sex,age,the histological type and differentiation,P0.05.There was a relation between MK and MVD in NSCLC,P0.05.CONCLUSION: MK can be a new mark of NSCLC,and served as an useful indicator in the assessment of metastases." @default.
- W2394224583 created "2016-06-24" @default.
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- W2394224583 date "2008-01-01" @default.
- W2394224583 modified "2023-10-06" @default.
- W2394224583 title "Expression of midkine and microvesseldensity in non-small cell lung cancer and significance" @default.
- W2394224583 hasPublicationYear "2008" @default.
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