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- W2394228591 abstract "Objective: To extract total saponins in Guizhou's Asparagi Radix( ASP) and observe the inhibitory effect of ASP on the HL-60 cells. Method: Effects of ASP on the cytoactive and apoptosis rate of HL-60 cells were investigated by MTT and flow cytometry. The expression of B cell lymphoma / leukemia-2( Bcl-2 mRNA in HL-60 cells was detected by method of Real-time PCR. Result: ASP could dose-dependently inhibit the cytoactive of HL-60 cells and improve significantly the apoptosis rate of HL-60 cells; The expression of Bcl-2 mRNA in HL-60 cells decreased significantly compared with blank group. Conclusion: ASP can decrease the expression of Bcl-2 mRNA and make HL-60 cells apoptosis,which maybe one of mechanisms of treating the human promyelocytic leukemia." @default.
- W2394228591 created "2016-06-24" @default.
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- W2394228591 date "2014-01-01" @default.
- W2394228591 modified "2023-09-22" @default.
- W2394228591 title "Inhibitory Effect of Total Saponins in Guizhou's Asparagi Radix on the Human Promyelocytic Leukemia HL-60 Cells" @default.
- W2394228591 hasPublicationYear "2014" @default.
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