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- W2394306903 abstract "Objective:Improved the sensitivity of tumors to chemotherapeutic drugs was the key to cancer treatment.Method: MTT assay,Atomic force microscope and Flow Cytometer were used to study tetrandrine combined with cisplatin on human breast cancer cell in vitro.Result:Inhibition of human breast cancer cell was treated with tetrandrine at different concentrations 48 hours.The concentration of tetrandrine at point of cell IC50 was 5.6μmol/l.When treated with cisplatin,the concentration was 26.33μmol/l.When treated with both of them,the concentration of tetrandrine was 2.5μmol/L,the other one was 13.32μmol/l.The surface of cell was damaged when treat with tetrandrine in low concentration at 24h and 48h.The S phase cell cycle percentage was improved to 51.7%±0.30%.Conclusion:Improved the sensitivity of tumors to chemotherapeutic drugs treatment,inhibit tumor growth." @default.
- W2394306903 created "2016-06-24" @default.
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- W2394306903 date "2011-01-01" @default.
- W2394306903 modified "2023-09-27" @default.
- W2394306903 title "Effects of Tetrandrine Combined with Cisplatin on Breast Cancer Cells in vitro" @default.
- W2394306903 hasPublicationYear "2011" @default.
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