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- W2394315635 abstract "Objective To explore the relation of a T-287C polymorphism in the 5′regulation region of tissue factor pathway inhibitor(TFPI) gene and acute myocardial infarction(AMI) in Hans of Northern China.Methods Eigty-two myocardial infarction patients(63 males and 19 females) recruited from the First Clinical College of Harbin Medical University during 2002～2004(AMI group).The control group consists of 110 presumably healthy subjects(82 males and 28 females) from routine health survey.All subjects were from Heilongjiang province and of the Han nationality.A polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP) assay was applied to analyse the TFPI T-287C polymorphism.Results The TFPI T-287C alleles frequencies of the AMI group and control healthy group were 0.9634,0.0366 and 0.9318,0.0682,respectively.The allele frequencies and genotype frequencies were consistent with the Hardy Weinberg law of equilibrium.There was no significant difference of allele frequencies and genotype frequencies between the two groups(P0.05,OR:0.6,95% CI:0.2～1.3).Conclusion There was no correlation between a T287C polymorphism in the 5′ regulation region of the TFPI gene and AMI in Hans of Northern China.The mutation of TFPI T287C gene was not the risk factor of AMI in Hans of Northern China,the frequencies of TFPI T287C alleles was wery low in Hans of Northern China." @default.
- W2394315635 created "2016-06-24" @default.
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- W2394315635 date "2009-01-01" @default.
- W2394315635 modified "2023-09-25" @default.
- W2394315635 title "Relationship between a T-287C polymorphism in the 5′regulation region of the tissue factor pathway inhibitor gene and acute myocardial infarction in Hans of Northern China" @default.
- W2394315635 hasPublicationYear "2009" @default.
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