Matches in SemOpenAlex for { <https://semopenalex.org/work/W2394327425> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2394327425 abstract "Objective To study the effect of hypertension on vascular structural and functional changes after removal of adventitia. Methods Rabbits( n =38), whose carotid artery adventitia was removed were randomly allocated into control group 1(as control) and group 2(norepinephrine was infused with osmotic minipumps). Seven days and 14 days after the operation, the intima and media were measured by image analyse system, vasotension changes were measured using a force transducer connected with a polygraph. mRNA expression were measured by RT-PCR. Results 1)The adventitia removal induced hyperplasia of intima which was most remaskable at day 14 in group 2( P 0.05). 2)Compared with intact vessel ring, norepinephrine (NE)-induced contraction of adventitia denuded vessel ring was less in group 1 at day 7, greater at day 14( P 0.05 or P 3) 14 days after operation, the expression of Rho-Kinase mRNA were increased in group 1( P 0.05)and in group 2( P 0.01). The expression of MCP-1 mRNA were increased in group 2(%P%0.01). Conclusions Hypertension enhanced the neointima formation and hyperreactivity of vascular vessels after removal of adventia. The mechanism of which may be ascnibed to activating of Rho-Kinase and MCP-1 in the vascular vessel wall." @default.
- W2394327425 created "2016-06-24" @default.
- W2394327425 creator A5091211890 @default.
- W2394327425 date "2003-01-01" @default.
- W2394327425 modified "2023-09-24" @default.
- W2394327425 title "Effect of Hypertension on Intima Proliferation and Vasoconstriction After Adventitia Removal" @default.
- W2394327425 hasPublicationYear "2003" @default.
- W2394327425 type Work @default.
- W2394327425 sameAs 2394327425 @default.
- W2394327425 citedByCount "0" @default.
- W2394327425 crossrefType "journal-article" @default.
- W2394327425 hasAuthorship W2394327425A5091211890 @default.
- W2394327425 hasConcept C126322002 @default.
- W2394327425 hasConcept C134018914 @default.
- W2394327425 hasConcept C164705383 @default.
- W2394327425 hasConcept C2776716733 @default.
- W2394327425 hasConcept C2776820930 @default.
- W2394327425 hasConcept C2777339539 @default.
- W2394327425 hasConcept C2777562237 @default.
- W2394327425 hasConcept C2778283817 @default.
- W2394327425 hasConcept C2778514916 @default.
- W2394327425 hasConcept C2778583881 @default.
- W2394327425 hasConcept C2779961880 @default.
- W2394327425 hasConcept C513476851 @default.
- W2394327425 hasConcept C71924100 @default.
- W2394327425 hasConceptScore W2394327425C126322002 @default.
- W2394327425 hasConceptScore W2394327425C134018914 @default.
- W2394327425 hasConceptScore W2394327425C164705383 @default.
- W2394327425 hasConceptScore W2394327425C2776716733 @default.
- W2394327425 hasConceptScore W2394327425C2776820930 @default.
- W2394327425 hasConceptScore W2394327425C2777339539 @default.
- W2394327425 hasConceptScore W2394327425C2777562237 @default.
- W2394327425 hasConceptScore W2394327425C2778283817 @default.
- W2394327425 hasConceptScore W2394327425C2778514916 @default.
- W2394327425 hasConceptScore W2394327425C2778583881 @default.
- W2394327425 hasConceptScore W2394327425C2779961880 @default.
- W2394327425 hasConceptScore W2394327425C513476851 @default.
- W2394327425 hasConceptScore W2394327425C71924100 @default.
- W2394327425 hasLocation W23943274251 @default.
- W2394327425 hasOpenAccess W2394327425 @default.
- W2394327425 hasPrimaryLocation W23943274251 @default.
- W2394327425 hasRelatedWork W1994296607 @default.
- W2394327425 hasRelatedWork W1998218655 @default.
- W2394327425 hasRelatedWork W2010000339 @default.
- W2394327425 hasRelatedWork W2019113284 @default.
- W2394327425 hasRelatedWork W2130486987 @default.
- W2394327425 hasRelatedWork W2145932955 @default.
- W2394327425 hasRelatedWork W2350688856 @default.
- W2394327425 hasRelatedWork W2352569979 @default.
- W2394327425 hasRelatedWork W2355916269 @default.
- W2394327425 hasRelatedWork W2368610918 @default.
- W2394327425 hasRelatedWork W2369847256 @default.
- W2394327425 hasRelatedWork W2369851510 @default.
- W2394327425 hasRelatedWork W2372222732 @default.
- W2394327425 hasRelatedWork W2372820404 @default.
- W2394327425 hasRelatedWork W2377054382 @default.
- W2394327425 hasRelatedWork W2382724995 @default.
- W2394327425 hasRelatedWork W2387863645 @default.
- W2394327425 hasRelatedWork W2391875735 @default.
- W2394327425 hasRelatedWork W2423566251 @default.
- W2394327425 hasRelatedWork W3147647979 @default.
- W2394327425 isParatext "false" @default.
- W2394327425 isRetracted "false" @default.
- W2394327425 magId "2394327425" @default.
- W2394327425 workType "article" @default.